Hardware support is pretty damn good now, but may require some research beforehand to ensure you get a system with no driver gotchas. Honestly, I have more trouble with driver setup on Windows than on Linux these days. That said, I won’t buy a computer that comes with any incompatibilities, so your experience may vary.
Gaming is easy on Linux now (assuming your system is set up properly) thanks to Steam’s Linux compatibility layer, which is built with WINE. They also have it on the Steam Deck, so you’ve actually probably used it already, you just didn’t know.
The only sticking point is Clip Studio Paint. Apparently it can be set up using WINE, but it’s not going to be as good as a native experience. Or at least, that would be my guess.