In a rational world this would completely shatter his chances for any presidential nomination from a major party (or probably the first indictment would)
However, there are a good number of people who believe so firmly in trump that they'll view this in exactly the same light as a left wing leader being arrested at a civil rights protest or admitting they smoked weed. To them this is a feather in his cap, it burnishes his credentials as being anti-establishment and proves whatever batshit conspiracy theories he's spouting.
I think democrats are too quick to overlook that risk and I think that's dangerous.