I could be wrong, but I think XRD requires very pure crystals of sufficiently large size. That can help you ascertain the structure and composition of something you can synthesize and crystalize, but I don't believe xrd can image specific regions of interest like single doping sites like this article talks about.
Synchrotron XRD also has a major drawback in having a very significant equipment requirement that requires being able send samples away for analysis at a dedicated facility. That puts limits on sample preparation and stability time, as well as sharing beam time with lots of other groups.
It's been a while since I've read up on synchrotron xray diffraction though, so there could be workarounds for some of those limitation or I could be misremembering details.