Another problem lies within the mathematical framework of the Standard Model itself—the Standard Model is inconsistent with that of general relativity, to the point that one or both theories break down under certain conditions (for example within known spacetime singularities like the Big Bang and the centres of black holes beyond the event horizon).[4]
My ELI5: Both theories work great, supported by vast amounts of evidence and excellent theoretical models. It seems they are two tools with distinct purposes. One for big and heavy stuff, the other for small and energetic stuff. The problem arises when big and heavy stuff is compressed into tiny spaces. This case is relevant for both theories, but here they don’t match, and we don’t know which to apply. It’s a strong hint we lack understanding, one of the biggest unsolved problems in physics.
So math itself is probably fine, we’re just at a loss how to use it in these extreme cases.