@orbitz@m4 From my experience, most DE specific apps will run under another DE. There are exceptions to this and sometimes the amount of dependencies etc needed makes you feel like you are installing much of the DE. Also, some DEs fundamentally use different schemes for launching and configuring settings which can be incompatible with other DEs. There are workarounds, etc but have their own headaches. Other people may have a different experience.
Gushing about KDE applications ( redstrate.com )