Since people have suggested virtual machines, I wanted to mention that most of them will not be using your GPU (and GPU passthrough is tricky), so they won't be helpful if you are using GPU-intensive apps.
On the other hand, moving form Adobe Illustrator to Inkscape was a pretty smooth transition for me, and I can't say I miss any of Adobe's features (except the Shape builder, which is also coming to Inkscape). However, I'm not a professional illustrator - it's mostly a hobby for me and I only use it for creating icons, simple illustrations and infographics
Gaming experience has been really good, though! (Steam/Proton and yuzu for emulating some Switch games)