Yeah, he was largely operating in safe space and still made some unethical decisions.
Janeway was willing to make the hard calls that would best serve her ship and it’s future, having your cook and your third in command get fused isn’t exactly going to result in a functioning chain of command.
Plus since the operation could be reversed, you could argue that Tuvok and Neelix aren’t actually dead, merely suspended animation like storing people in a transporter buffer. You’re still killing Tuvix, but sacrificing one to save two is “the needs of the many” in it’s most simplistic form even without the added weight of hundreds of lives depending on Tuvok’s leadership and tactical skills.
I never once considered Janeway to be out of line given her circumstances. The crew always comes first even at the cost of her own humanity and ethics. She’s a good captain, willing to make the call that ends lives and live with it so that others may not have to endure those decisions and consequences. She didn’t ask anyone else to do that for her.