Using Manjaro KDE here, as well. Granted, I mostly play Counter-Strike, Risk of Rain 2, Stellaris, and various indie games, but pretty much everything has been very smooth. Very glad to be free of Windows on my main machine, and it hasn't really affected how I use my PC day-to-day.
It is doable to install an OS onto a flash drive or external drive, but from my experience it was really slow. Just need to make sure to then boot the machine to the USB device. Some machines you might find it difficult to change that in the BIOS.
Mint for my desktop, SteamOS on Deck. Both do what I need, and the only issues I've run into since switching have been random things like GOG not having an updated Planescape Torment build that works out of the box. I don't play many online competitive games with like invasive anti-cheat stuff, so I haven't run into a ton of compatibility issues.
I'm using Nobara. It's a gaming tweaked Fedora with a bunch of gaming and steaming related software preinstalled and configured. Works well in my experience.
Same, started using it on a pc connected to my tv (for a console like experience, boots straight into gamescope/steam).
Now I also use it on my desktop (replacing Ubuntu).
Debian Stable + Backports, with a few customized flatpaks. I don’t care that my desktop apps are not bleeding edge. My system always works, and games run great.
The way it was explained to me was Fedora = RHEL Alpha, CentOS Stream = RHEL Beta, RHEL is Stable, then there are downstreams who build against RHEL. Only those who are downstream of REHL are effected by the changes. Both Fedora and Cent are necessary development platforms to support everything that eventually makes it down to RHEL in stable condition. They both depend on RHEL for funding, but RHEL depends on them for testing.
I've been using PopOS and Steam installed in Flatpak, as well as native and both have worked really well. Lutris i have installed through flatpak, as otherwise it sometimes gave me issues. This is running really well on my AMD 5950x and 6800XT
You can use ubuntu, debian, or a few other live distros with "persistence" which is relatively easy to configure. This is neat because live versions usually come with cool features like auto configuration of devices and displays. You can even create a persistence boot of live isos on ventoy, which is honestly what I'd recommend.
I think you can simply install a Linux distro on a USB drive. You should use something fast like a USB-C hard drive and you’ll have to think about where to put the boot loader. But if you’re careful, what you have in mind should work.
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